Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368196 | 0.82 | CTSK (0.42) | CTSKFAAHTRPV1FABP4FABP5 | |
| SCHEMBL13624184 | 0.81 | CTSL (0.42) | CTSKFABP4FABP5 | |
| SCHEMBL23693804 | 0.68 | CTSK (0.33) | CTSK | |
| SCHEMBL1837046 | 0.67 | KCNK3 (0.44) | CTSKERAP1 | |
| SCHEMBL2156068 | 0.65 | CTSK (0.66) | CTSK | |
| SCHEMBL5870313 | 0.63 | ALDH1A1 (0.40) | CTSKFAAHTRPV1USP2HTT | |
| SCHEMBL8257823 | 0.63 | ALDH1A1 (0.40) | CTSKFAAHTRPV1USP2HTT | |
| SCHEMBL12869545 | 0.61 | ALDH1A1 (0.36) | CTSKUSP2HTTSMN1; SMN2CYP1A2 | |
| SCHEMBL25152543 | 0.61 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL29154166 | 0.60 | CYP1A2 (0.43) | CTSKFAAHUSP2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |