Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367407 | 0.81 | MCL1 (1.00) | MCL1CA1CA2MAP1LC3BTYMS | |
| SCHEMBL14922764 | 0.81 | MCL1 (0.70) | MCL1CA1CA2MAP1LC3BCYP1A2 | |
| SCHEMBL13302005 | 0.80 | MCL1 (0.43) | MCL1RPS6KA3JAK3 | |
| SCHEMBL13694210 | 0.80 | MCL1 (0.65) | MCL1CA1CA2MAP1LC3B | |
| SCHEMBL13302003 | 0.78 | MCL1 (0.71) | MCL1CA1CA2MAP1LC3B | |
| SCHEMBL14922765 | 0.67 | MCL1 (0.67) | MCL1CA1CA2TYMSCYP1A2 | |
| SCHEMBL14153894 | 0.66 | KIF11 (0.44) | MCL1 | |
| SCHEMBL12113984 | 0.66 | MCL1 (0.53) | MCL1 | |
| SCHEMBL15229667 | 0.64 | MCL1 (0.67) | MCL1CA1CA2MAP1LC3BCYP1A2 | |
| SCHEMBL15229541 | 0.64 | MCL1 (0.67) | MCL1CA1CA2MAP1LC3BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745083-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090297218-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2009-12-03 | — | — | US | disclosed |
| US-7396622-B2 | Having a charge generation layer containing a phenanthrene compound, a phenanthroline compound or an acenaphthene compound that has two oxo-, phenylimino- or dicyanovinylene groups that may be the same or different; charge-generating material is preferably hydroxygallium phthalocyanine. | CANON KABUSHIKI KAISHA (JP) | 2008-07-08 | — | — | US | disclosed |