Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302002 | 0.80 | MCL1 (0.67) | MCL1CA1CA2MAP1LC3B | |
| SCHEMBL2367407 | 0.80 | MCL1 (1.00) | MCL1KDM4ETDP1CA1CA2 | |
| SCHEMBL14922764 | 0.80 | MCL1 (0.70) | MCL1KDM4ETDP1CA1CA2 | |
| SCHEMBL13302003 | 0.77 | MCL1 (0.71) | MCL1CA1CA2MAP1LC3B | |
| SCHEMBL14922765 | 0.66 | MCL1 (0.67) | MCL1KDM4ETDP1CA1CA2 | |
| SCHEMBL16601998 | 0.66 | MCL1 (0.47) | MCL1 | |
| SCHEMBL12113984 | 0.65 | MCL1 (0.53) | MCL1KDM4E | |
| SCHEMBL16602012 | 0.65 | MCL1 (0.52) | MCL1 | |
| SCHEMBL16602007 | 0.65 | MCL1 (0.56) | MCL1 | |
| SCHEMBL16602019 | 0.63 | MCL1 (0.53) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592113-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080233499-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-09-25 | — | — | US | disclosed |