SCHEMBL13302003

SCHEMBL13302003

N#CC(C#N)=c1c(=O)c2cccc3cc(N=O)cc1c32

nearest known ligand 0.71

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MCL1 Q07820 5/20 0.71
▸ MAP1LC3B Q9GZQ8 1/20 0.34
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367407 0.84 MCL1 (1.00) MCL1MAP1LC3BCA1CA2
SCHEMBL14922764 0.81 MCL1 (0.70) MCL1MAP1LC3BCA1CA2
SCHEMBL13302002 0.78 MCL1 (0.67) MCL1MAP1LC3BCA1CA2
SCHEMBL13694210 0.77 MCL1 (0.65) MCL1MAP1LC3BCA1CA2
SCHEMBL15229541 0.67 MCL1 (0.67) MCL1MAP1LC3BCA1CA2
SCHEMBL14922765 0.67 MCL1 (0.67) MCL1CA1CA2
SCHEMBL15229667 0.67 MCL1 (0.67) MCL1MAP1LC3BCA1CA2
SCHEMBL12113984 0.66 MCL1 (0.53) MCL1
SCHEMBL29433737 0.64 MCL1 (0.58) MCL1MAP1LC3BCA1CA2
SCHEMBL15243620 0.63 MCL1 (0.60) MCL1MAP1LC3BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7745083-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-06-29 — — US disclosed
US-20090297218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-12-03 — — US disclosed
US-7592113-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-09-22 — — US disclosed
US-20080233499-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-09-25 — — US disclosed
US-7396622-B2 Having a charge generation layer containing a phenanthrene compound, a phenanthroline compound or an acenaphthene compound that has two oxo-, phenylimino- or dicyanovinylene groups that may be the same or different; charge-generating material is preferably hydroxygallium phthalocyanine. CANON KABUSHIKI KAISHA (JP) 2008-07-08 — — US disclosed
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