⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35106 | 0.82 | MEN1 (0.30) | — | |
| SCHEMBL632195 | 0.77 | — | — | |
| SCHEMBL1618458 | 0.73 | — | — | |
| SCHEMBL868123 | 0.72 | — | — | |
| SCHEMBL1618688 | 0.71 | — | — | |
| SCHEMBL18043776 | 0.66 | PTGER4 (0.31) | — | |
| SCHEMBL5448930 | 0.62 | PKM (0.31) | — | |
| SCHEMBL20526212 | 0.62 | MMP9 (0.30) | — | |
| SCHEMBL15876106 | 0.60 | NPC1 (0.41) | — | |
| SCHEMBL17506022 | 0.58 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |