Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368004 | 0.95 | PPARG (0.39) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL2367752 | 0.89 | PPARG (0.34) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL2367340 | 0.88 | BACE1 (0.33) | PPARGPPARAPPARDMAPTGPR84 | |
| SCHEMBL2367563 | 0.84 | BACE1 (0.42) | PPARGPPARDKDM4EALDH1A1MAPT | |
| SCHEMBL12539335 | 0.81 | RAB9A (0.43) | — | |
| SCHEMBL19689391 | 0.80 | KIF11 (0.38) | HTTLMNA | |
| SCHEMBL16618219 | 0.80 | CYP1A2 (0.38) | CYP2C19HTTBACE1LMNA | |
| SCHEMBL19463046 | 0.80 | KIF11 (0.43) | — | |
| SCHEMBL16618237 | 0.78 | MAOB (0.47) | PPARDMAPT | |
| SCHEMBL16624846 | 0.77 | BACE1 (0.42) | PPARDABL1ABCB1BCRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366785-B1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT, AND USE OF THE LABELING AGENT | JAPAN SCIENCE & TECH AGENCY (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8354515-B2 | Oligonucleotide derivative, labeling agent and use for labeling agent | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20120126175-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT AND USE FOR LABELING AGENT | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-05-24 | — | — | US | disclosed |
| EP-2366785-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT, AND USE OF THE LABELING AGENT | Japan Science And Technology Agency (JP) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010055789-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT, AND USE OF THE LABELING AGENT | 独立行政法人科学技術振興機構 (JP) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126175-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT AND USE FOR LABELING AGENT | UPF1, SPIN4, SRRT | PPARG 1343/4885PPARA 1658/4885CYP2C9 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.