Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367340 | 0.93 | BACE1 (0.33) | PPARGPPARAGPR84PPARDACACA | |
| SCHEMBL2367722 | 0.89 | PPARG (0.43) | PPARGPPARAGPR84PPARDACACA | |
| SCHEMBL2368004 | 0.89 | PPARG (0.39) | PPARGPPARAGPR84PPARDACACA | |
| SCHEMBL2367563 | 0.80 | BACE1 (0.42) | PPARGPPARDBACE1MAPTSLC6A1 | |
| SCHEMBL12539335 | 0.77 | RAB9A (0.43) | SLC6A1SLC6A11 | |
| SCHEMBL13365235 | 0.77 | CYP1A2 (0.36) | PPARGPPARAPPARDMAPTMAPK1 | |
| SCHEMBL16618219 | 0.76 | CYP1A2 (0.38) | BACE1CYP2C19SLC6A1SLC6A11 | |
| SCHEMBL19463046 | 0.76 | KIF11 (0.43) | SLC6A1SLC6A11 | |
| SCHEMBL19689391 | 0.76 | KIF11 (0.38) | SLC6A1SLC6A11 | |
| SCHEMBL16618237 | 0.75 | MAOB (0.47) | PPARDPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366785-B1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT, AND USE OF THE LABELING AGENT | JAPAN SCIENCE & TECH AGENCY (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-8354515-B2 | Oligonucleotide derivative, labeling agent and use for labeling agent | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20120126175-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT AND USE FOR LABELING AGENT | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-05-24 | — | — | US | disclosed |
| EP-2366785-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT, AND USE OF THE LABELING AGENT | Japan Science And Technology Agency (JP) | 2011-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120126175-A1 | OLIGONUCLEOTIDE DERIVATIVE, LABELING AGENT AND USE FOR LABELING AGENT | UPF1, SPIN4, SRRT | PPARG 1343/4885PPARA 1658/4885GPR84 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.