Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24183747 | 0.86 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL24982400 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL23515744 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL23680214 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL23680331 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL23718734 | 0.74 | LMNA (0.39) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL25975953 | 0.74 | NPC1 (0.47) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL25608795 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AHTR1ADRD2 | |
| SCHEMBL23106052 | 0.72 | AKT1 (0.47) | ALDH1A1SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL20787950 | 0.71 | FAAH (0.50) | ALDH1A1SMN1; SMN2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854816-A1 | ANTI-B7H3 ANTIBODY-EXATECAN ANALOG CONJUGATE AND MEDICINAL USE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |