Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | FRK | P42685 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | NEK4 | P51957 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501721 | 1.00 | EGFR (0.34) | EGFRPRKACAFRKGSK3AGSK3B | |
| SCHEMBL23680932 | 0.91 | MEN1 (0.37) | KDM4EHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29501726 | 0.90 | HTR1A (0.38) | KCNA3ATMHTR1AADRA1DADRA1A | |
| SCHEMBL23680921 | 0.90 | HTR1A (0.38) | KCNA3ATMHTR1AADRA1DADRA1A | |
| SCHEMBL23672523 | 0.89 | KCNA3 (0.31) | TDP1KCNA3MEN1KMT2AHTR1A | |
| SCHEMBL29501779 | 0.89 | KCNA3 (0.31) | TDP1KCNA3MEN1KMT2AHTR1A | |
| SCHEMBL23672521 | 0.89 | KCNA3 (0.31) | TDP1KCNA3MEN1KMT2AHTR1A | |
| SCHEMBL23680929 | 0.85 | MET (0.33) | EGFRFRKKCNA3HTR1AADRA1D | |
| SCHEMBL23680928 | 0.85 | TP53 (0.34) | MAPTNPC1LMNAHTTATM | |
| SCHEMBL29501723 | 0.85 | MET (0.33) | EGFRFRKKCNA3HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210227826-A1 | Microbiocidal Picolinamide Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210227826-A1 | Microbiocidal Picolinamide Derivatives | CASP2, CASP1, MSR1 | EGFR 4651/4885PRKACA 3428/4885FRK 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.