SCHEMBL29501779

SCHEMBL29501779

COc1ccnc(C(=O)N[C@@H](C)C(=O)OC2CCC2(c2ccc(C)cc2)c2ccc(C)cc2)c1O

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.31
XBP1 P17861 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
NTRK3 Q16288 1/20 0.30
SRPK1 Q96SB4 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CTSA P10619 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23672521 1.00 KCNA3 (0.31) KCNA3XBP1TDP1HTR1AADRA1D
SCHEMBL23672523 1.00 KCNA3 (0.31) KCNA3XBP1TDP1HTR1AADRA1D
SCHEMBL29501723 0.92 MET (0.33) KCNA3HTR1AADRA1DADRA1AADRA1B
SCHEMBL29501780 0.92 TP53 (0.34) HTR1AADRA1DADRA1AADRA1B
SCHEMBL23680929 0.92 MET (0.33) KCNA3HTR1AADRA1DADRA1AADRA1B
SCHEMBL23680928 0.92 TP53 (0.34) HTR1AADRA1DADRA1AADRA1B
SCHEMBL29501726 0.92 HTR1A (0.38) KCNA3HTR1AADRA1DADRA1AADRA1B
SCHEMBL23680921 0.92 HTR1A (0.38) KCNA3HTR1AADRA1DADRA1AADRA1B
SCHEMBL23680945 0.89 EGFR (0.34) KCNA3TDP1HTR1AADRA1DADRA1A
SCHEMBL29501721 0.89 EGFR (0.34) KCNA3TDP1HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710429-B1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-04-05 EP disclosed
US-11291205-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291205-B2 Microbiocidal picolinamide derivatives CASP2, CASP1, MSR1 KCNA3 1289/4885XBP1 4089/4885TDP1 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.