SCHEMBL2368336

SCHEMBL2368336

c1cnn(B(n2cccn2)n2cccn2)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.34
NOS1 P29475 1/20 0.33
FBP1 P09467 1/20 0.32
KDM4E B2RXH2 3/20 0.31
ALDH1A1 P00352 3/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
G6PD P11413 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055343 0.97 NOTUM (0.33) NOTUMNOS1FBP1KDM4EALDH1A1
SCHEMBL3897073 0.97 NOTUM (0.33) NOTUMNOS1FBP1KDM4EALDH1A1
SCHEMBL4053334 0.97 NOTUM (0.33) NOTUMNOS1FBP1KDM4EALDH1A1
SCHEMBL18872139 0.77 MAPT (0.35) NOTUMNOS1KDM4EALDH1A1GAA
SCHEMBL14959656 0.77
SCHEMBL130328 0.77
SCHEMBL12136634 0.77 NOTUM (0.32) NOTUMNOS1FBP1
SCHEMBL29209440 0.75
SCHEMBL20088981 0.73
SCHEMBL17210860 0.71 FDPS (0.34) NOTUMNOS1KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3625218-B1 PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-03-01 EP claimed
EP-2274312-B1 METAL COMPLEXES UNIV ZUERICH (CH) 2015-06-03 EP claimed
EP-2708547-A1 AQUEOUS SOLUTIONS OF RADIOMETAL COMPLEXES WITH TRIDENTATE LIGENDS Universität Zürich (CH) 2014-03-19 EP claimed
US-20110230456-A1 Nitridoosmium(VI) Complexes for Treatment of Cancer THE CITY UNIVERSITY OF HONG KONG (HK) 2011-09-22 US claimed
US-20110065680-A1 Metal Complexes UNIVERSITY OF ZURICH (CH) 2011-03-17 US claimed
US-12063788-B2 Thin film molecular memory NUTECH VENTURES (US) 2024-08-13 US disclosed
US-11827653-B2 Tridentate macrocyclic compounds THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-11-28 US disclosed
US-11827653-B2 Tridentate macrocyclic compounds THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-11-28 US disclosed
US-11653557-B2 Organic electronic device NOVALED GMBH (DE) 2023-05-16 US disclosed
US-20230128732-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
EP-3399568-B1 ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2023-03-22 EP disclosed
EP-3625218-B1 PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2023-03-01 EP disclosed
EP-0792252-A1 MONOMERS AND COMPOSITION WHICH CAN BE CROSSLINKED AND CROSSLINKED POLYMERS Ciba SC Holding AG (CH) 1997-09-03 EP disclosed
EP-0729485-A1 PROCESS FOR THE POLYMERISATION OF CYCLIC OLEFINS AND PHOTOPOLYMERISABLE COMPOSITION Ciba SC Holding AG (CH) 1996-09-04 EP disclosed
WO-1996024629-A1 POLYMERISABLE COMPOSITION, PROCESS FOR PRODUCING CROSS-LINKED POLYMERS, AND CROSS-LINKABLE POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-08-15 WO disclosed
WO-1996019540-A1 POLYMERISABLE ACETYLENE COMPOSITION AND ACETYLENE PHOTOPOLYMERISATION PROCESS CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 1996-06-27 WO disclosed
WO-1996016105-A1 PROCESS FOR POLYMERIZING CYCLICAL OLEFINS AND PHOTOPOLYMERIZABLE COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-05-30 WO disclosed
WO-1996016102-A1 PROCESS FOR THE THERMAL POLYMERIZATION OF CYCLICAL OLEFINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-05-30 WO disclosed
WO-1996016008-A1 MONOMERS AND COMPOSITION WHICH CAN BE CROSSLINKED AND CROSSLINKED POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-05-30 WO disclosed
WO-1995014051-A1 PROCESS FOR THE POLYMERISATION OF CYCLIC OLEFINS AND PHOTOPOLYMERISABLE COMPOSITION CIBA-GEIGY AG (CH) 1995-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230456-A1 Nitridoosmium(VI) Complexes for Treatment of Cancer NPM1, IDH2, MT-ND5 NOTUM 1181/4885NOS1 85/4885FBP1 3255/4885
US-20110065680-A1 Metal Complexes CLTA, L3MBTL3, CLTB NOTUM 4124/4885NOS1 4085/4885FBP1 3693/4885
US-11827653-B2 Tridentate macrocyclic compounds CBR3, NOX3, CYB5R3 NOTUM 1727/4885NOS1 292/4885FBP1 3126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.