Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260159 | 1.00 | SLC7A5 (0.41) | SLC7A5CASRSRD5A1TDP1STAT3 | |
| SCHEMBL23684304 | 0.79 | UNG (0.53) | SRD5A1TDP1P4HBLMNA | |
| SCHEMBL895414 | 0.76 | UNG (0.56) | SLC7A5TDP1STAT3P4HBGRIN2D | |
| SCHEMBL6392515 | 0.75 | GRM5 (0.45) | SRD5A1TDP1P4HBGRIN2DGRIN3B | |
| SCHEMBL31487534 | 0.75 | SLC7A5 (0.48) | SLC7A5TDP1STAT3P4HBGRIN2D | |
| SCHEMBL2948778 | 0.75 | TDP1 (0.53) | TDP1P4HBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL15496946 | 0.75 | SLC7A5 (0.48) | SLC7A5TDP1STAT3P4HBGRIN2D | |
| SCHEMBL110296 | 0.73 | SLC7A5 (0.58) | SLC7A5SRD5A1TDP1STAT3GABRA1 | |
| SCHEMBL5732625 | 0.73 | LMNA (0.38) | SRD5A1TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20299500 | 0.73 | TUBB4A (0.49) | SLC7A5TDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | XDH, F12, LPXN | SLC7A5 2181/4885CASR 2994/4885SRD5A1 320/4885 |
| US-11077101-B1 | Compounds and methods of use | XDH, F12, LPXN | SLC7A5 2181/4885CASR 2994/4885SRD5A1 320/4885 |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | XDH, F12, LPXN | SLC7A5 2181/4885CASR 2994/4885SRD5A1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.