Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 4/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161452 | 0.84 | SRD5A1 (0.60) | UNGSRD5A1KMOTTRFBP1 | |
| SCHEMBL17982828 | 0.81 | SRD5A1 (0.46) | UNGSRD5A1KMOTTRFBP1 | |
| SCHEMBL23684239 | 0.79 | SLC7A5 (0.41) | SRD5A1TDP1LMNAP4HB | |
| SCHEMBL2277720 | 0.77 | ALDH1A1 (0.41) | UNGTDP1MAPTCA12CA1 | |
| SCHEMBL14931462 | 0.76 | UNG (0.50) | UNGSRD5A1KMOTTRFBP1 | |
| SCHEMBL5732625 | 0.76 | LMNA (0.38) | SRD5A1TDP1LMNACYP2C9 | |
| SCHEMBL16053002 | 0.75 | ALDH1A1 (0.47) | TDP1LMNAMAPTRAB9ASMN1; SMN2 | |
| Isophthalic Acid SCHEMBL6410358 | 0.74 | KMO (0.61) | UNGKMOTDP1LMNAMAPT | |
| Isophthalic Acid SCHEMBL9136669 | 0.73 | KMO (0.59) | UNGKMOTDP1LMNAMAPT | |
| SCHEMBL8899992 | 0.72 | TTR (0.79) | UNGSRD5A1KMOTTRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11077101-B1 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11986471-B2 | Compounds and methods of use | XDH, F12, LPXN | UNG 3774/4885SRD5A1 320/4885KMO 2774/4885 |
| US-11077101-B1 | Compounds and methods of use | XDH, F12, LPXN | UNG 3774/4885SRD5A1 320/4885KMO 2774/4885 |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | XDH, F12, LPXN | UNG 3774/4885SRD5A1 320/4885KMO 2774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.