Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417240 | 0.89 | CYP19A1 (0.46) | CYP19A1ALOX5CYP3A4USP2NPC1 | |
| SCHEMBL27417237 | 0.82 | ALOX5 (0.51) | CYP19A1ALOX5CYP3A4USP2 | |
| SCHEMBL3431006 | 0.80 | ALOX5 (0.44) | CYP19A1ALOX5CYP3A4HTTMAPT | |
| SCHEMBL31544955 | 0.77 | ALOX5 (0.49) | CYP19A1ALOX5CYP3A4NPC1HPGD | |
| SCHEMBL3904790 | 0.77 | CA2 (0.39) | CYP3A4USP2DHODHMAPT | |
| SCHEMBL3915407 | 0.77 | OPRM1 (0.57) | CYP3A4USP2MAPTPPARA | |
| SCHEMBL3902347 | 0.77 | CA2 (0.39) | CYP3A4USP2DHODHMAPT | |
| SCHEMBL3904168 | 0.77 | CA2 (0.39) | CYP3A4USP2DHODHMAPT | |
| SCHEMBL3909497 | 0.77 | CA2 (0.39) | CYP3A4USP2DHODHMAPT | |
| SCHEMBL5141874 | 0.76 | ALOX5 (0.46) | ALOX5CYP3A4USP2MAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228531-A1 | TARGETED TREATMENT OF AUTISM SPECTRUM DISORDER AND OTHER NEUROLOGICAL OR PSYCHIATRIC DISORDERS | AUTTX, LLC | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228531-A1 | TARGETED TREATMENT OF AUTISM SPECTRUM DISORDER AND OTHER NEUROLOGICAL OR PSYCHIATRIC DISORDERS | HNRNPL, HNRNPLL, HNRNPA1 | CYP19A1 2334/4885ALOX5 1273/4885CYP3A4 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.