Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686901 | 0.89 | CYP19A1 (0.45) | CYP19A1NPC1HPGDMAPK1HTT | |
| SCHEMBL27417237 | 0.84 | ALOX5 (0.51) | CYP19A1ALOX5USP2CYP3A4 | |
| SCHEMBL3431006 | 0.75 | ALOX5 (0.44) | CYP19A1HTTALOX5KAT8PPARA | |
| Flavoglaucin SCHEMBL30431735 | 0.75 | OPRM1 (0.63) | CYP19A1PPARA | |
| SCHEMBL30640325 | 0.74 | CYP19A1 (0.53) | CYP19A1NPC1HPGDMAPK1HTT | |
| SCHEMBL2459346 | 0.74 | CYP19A1 (0.40) | CYP19A1NPC1HPGDMAPK1HTT | |
| SCHEMBL5899688 | 0.73 | TYR (0.55) | HTTALOX5KAT8PPARAKDM4E | |
| SCHEMBL9018867 | 0.73 | OPRD1 (0.41) | CYP19A1HPGDHTTALOX5KDM4E | |
| SCHEMBL10716857 | 0.73 | HIF1A (0.43) | CYP19A1GPR84 | |
| SCHEMBL8422212 | 0.72 | TYR (0.54) | HTTALOX5KAT8PPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024124203-A2 | TARGETED TREATMENT OF SPLICEOPATHY-INDUCED NEUROLOGICAL DISORDERS | AUTTX, LLC (US) | 2024-06-13 | — | — | WO | disclosed |