Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 5/20 | 0.69 |
| ▸ | PRKCI | P41743 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FER | P16591 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386676 | 0.82 | PRKCZ (1.00) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL13837726 | 0.82 | PRKCZ (1.00) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL13837635 | 0.81 | PRKCZ (1.00) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL985717 | 0.76 | RORB (0.64) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL13838083 | 0.75 | PRKCZ (0.61) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL2368850 | 0.74 | ALDH1A1 (0.50) | PRKCZPRKCIMAPTHSD17B10ALDH1A1 | |
| SCHEMBL20635749 | 0.74 | PRKCZ (0.87) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL27469272 | 0.74 | PRKCZ (0.48) | PRKCZPRKCIMAPTHSD17B10ALOX15 | |
| SCHEMBL8188234 | 0.73 | KMT2A (0.65) | PRKCZPRKCIMAPTHSD17B10HTT | |
| SCHEMBL15940345 | 0.73 | PRKCZ (0.58) | PRKCZPRKCIMAPTHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022076-B2 | Thieno[2,3-d]pyrimidine derivatives as potassium channel modulators; antiarrhythmia agents | XENTION LIMITED (GB) | 2011-09-20 | — | — | US | disclosed |
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | PRKCZ 2857/4885PRKCI 2326/4885MAPT 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.