Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850695 | 0.84 | PRKCZ (0.66) | PRKCZPRKCIGRM6ALDH1A1HPGD | |
| SCHEMBL5212225 | 0.82 | RIPK2 (0.46) | PRKCZPRKCIGRM6ALDH1A1HPGD | |
| SCHEMBL27461391 | 0.76 | GRM6 (0.60) | GRM6ALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL5245843 | 0.76 | MAPT (0.54) | PRKCZPRKCIALDH1A1HPGDKDM4E | |
| SCHEMBL7957161 | 0.74 | GRM6 (0.77) | GRM6ALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL2369127 | 0.74 | PRKCZ (0.69) | PRKCZPRKCIALDH1A1HPGDKDM4E | |
| SCHEMBL13216170 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EPKMNPSR1 | |
| SCHEMBL7207512 | 0.72 | GRM6 (0.71) | GRM6ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL3909728 | 0.72 | PTPN1 (0.47) | SMN1; SMN2 | |
| SCHEMBL3384951 | 0.70 | PRKCZ (0.66) | PRKCZPRKCIGRM6ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106663-A | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-16 | — | — | CN | disclosed |