Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177 | 1.00 | TSHR (0.39) | TSHRALDH1A1DNM1HTR2AHRH1 | |
| SCHEMBL3826312 | 0.95 | TSHR (0.39) | TSHRALDH1A1DNM1HTR2AHRH1 | |
| SCHEMBL22739910 | 0.95 | TSHR (0.39) | TSHRALDH1A1DNM1HTR2AHRH1 | |
| SCHEMBL182026 | 0.95 | TSHR (0.39) | TSHRALDH1A1DNM1HTR2AHRH1 | |
| SCHEMBL3928045 | 0.93 | TSHR (0.38) | TSHRALDH1A1DNM1HTR2AHRH1 | |
| SCHEMBL19699299 | 0.92 | MAPT (0.42) | TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL22166093 | 0.92 | HTR2A (0.37) | TSHRALDH1A1HTR2AHRH1USP2 | |
| SCHEMBL16843407 | 0.92 | DNM1 (0.43) | TSHRALDH1A1DNM1KDM4ETDP1 | |
| SCHEMBL28289558 | 0.92 | ALDH1A1 (0.34) | TSHRALDH1A1CYP1A2HRH2HRH4 | |
| SCHEMBL23899119 | 0.92 | DNM1 (0.38) | TSHRALDH1A1DNM1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210735-A1 | PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL | FIRMENICH SA (CH) | 2023-07-06 | — | — | US | disclosed |
| EP-4164587-A1 | PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL | Firmenich SA (CH) | 2023-04-19 | — | — | EP | disclosed |
| WO-2021250130-A1 | PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL | FIRMENICH SA (CH) | 2021-12-16 | — | — | WO | disclosed |
| EP-3856358-A2 | PREVENTION OF THE OXIDATION OF PERFUMERY RAW MATERIALS AND FOOD RAW MATERIALS | Firmenich SA (CH) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210735-A1 | PREVENTION, REDUCTION, OR AMELIORATION OF OLD PERSON SMELL | ACHE, RBP4, LPO | TSHR 4467/4885ALDH1A1 493/4885DNM1 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.