Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474533 | 0.81 | ACHE (0.46) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL31417620 | 0.81 | SOS1 (0.50) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL23698877 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDPOLBL3MBTL1MAPK1 | |
| SCHEMBL31417527 | 0.79 | ACHE (0.36) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL21367478 | 0.79 | KMT2A (0.44) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL31417550 | 0.78 | ACHE (0.36) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL23698910 | 0.77 | KDM4E (0.38) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL3709174 | 0.76 | HSD17B10 (0.49) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL18397725 | 0.76 | SLC6A3 (0.40) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL20636626 | 0.73 | KDM4E (0.44) | ALDH1A1KDM4EHPGDNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162864-B2 | Condensed-cyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-12-10 | — | — | US | disclosed |
| EP-3858823-A1 | CONDENSED-CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2021-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162864-B2 | Condensed-cyclic compound | SLC10A2, VIP, AVPR2 | ALDH1A1 1810/4885KDM4E 2962/4885HPGD 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.