Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699399 | 0.90 | TAAR1 (0.42) | PPARATAAR1HSD17B2MEN1KMT2A | |
| SCHEMBL16798383 | 0.86 | LDHA (0.51) | PPARAKMT2APPARG | |
| SCHEMBL23699429 | 0.85 | CYP1A2 (0.51) | CYP1A2FOLH1 | |
| SCHEMBL23699358 | 0.85 | CTSS (0.47) | PPARASLC7A5MAOBMEN1KMT2A | |
| SCHEMBL23699440 | 0.82 | FOLH1 (0.56) | SLC7A5MAOBFOLH1 | |
| SCHEMBL2026436 | 0.81 | PPARA (0.48) | PPARATAAR1SLC7A5CYP1A2MEN1 | |
| SCHEMBL2026435 | 0.81 | PPARA (0.48) | PPARATAAR1SLC7A5CYP1A2MEN1 | |
| SCHEMBL25251768 | 0.79 | AOC3 (0.45) | BCHEACHE | |
| SCHEMBL3010321 | 0.78 | AOC3 (0.56) | TAAR1HSD17B2BCHEACHE | |
| SCHEMBL16798442 | 0.77 | CTSS (0.44) | PPARACYP1A2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |