Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699431 | 0.86 | MAOB (0.42) | FOLH1MAOBCTSSCTSKCTSB | |
| SCHEMBL23699429 | 0.84 | CYP1A2 (0.51) | FOLH1SLC6A4 | |
| SCHEMBL23699358 | 0.83 | CTSS (0.47) | FOLH1MAOBSLC7A5CTSSCTSK | |
| SCHEMBL25182974 | 0.82 | FOLH1 (0.49) | FOLH1MAOBSLC7A5CTSSCTSK | |
| SCHEMBL23699341 | 0.82 | PPARA (0.45) | FOLH1MAOBSLC7A5 | |
| SCHEMBL1915526 | 0.82 | FOLH1 (0.60) | FOLH1MAOBSLC7A5CTSSCTSK | |
| SCHEMBL1915530 | 0.82 | FOLH1 (0.60) | FOLH1MAOBSLC7A5CTSSCTSK | |
| SCHEMBL320434 | 0.81 | MEP1A (0.49) | FOLH1MAOBCTSSCTSBCTSL | |
| SCHEMBL23699405 | 0.79 | MAOB (0.41) | MAOBCTSSCTSKCTSBCTSL | |
| SCHEMBL25956546 | 0.78 | FOLH1 (0.47) | FOLH1MAOBSLC7A5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |