Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699429 | 0.86 | CYP1A2 (0.51) | SLC1A1HPGDATMFOLH1HTR2C | |
| SCHEMBL16798442 | 0.85 | CTSS (0.44) | CTSSCTSKRIPK1PPARGPPARA | |
| SCHEMBL23699341 | 0.85 | PPARA (0.45) | MEN1KMT2ASLC7A5PPARGPPARA | |
| SCHEMBL23699440 | 0.83 | FOLH1 (0.56) | CTSSCTSKSLC7A5MAOBFOLH1 | |
| SCHEMBL16798266 | 0.82 | PPARA (0.40) | SLC7A5PPARGPPARAHTR2CSLC6A4 | |
| SCHEMBL25185803 | 0.81 | CTSS (0.49) | CTSSCTSKRIPK1SLC1A1MEN1 | |
| SCHEMBL1915346 | 0.81 | CTSS (0.51) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL1915348 | 0.81 | CTSS (0.51) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL23699386 | 0.80 | CTSS (0.47) | CTSSCTSKRIPK1MEN1KMT2A | |
| SCHEMBL16798328 | 0.78 | KMT2A (0.43) | KMT2APPARGPPARAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |