Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699429 | 0.84 | CYP1A2 (0.51) | ATMHTR2CSLC6A4 | |
| SCHEMBL23699405 | 0.82 | MAOB (0.41) | CTSSCTSKPTPN1SLC6A4 | |
| SCHEMBL16798442 | 0.81 | CTSS (0.44) | CTSSCTSKRIPK1PPARGPPARA | |
| SCHEMBL30192155 | 0.81 | CTSS (0.49) | CTSSCTSKRIPK1PTPN1PPARG | |
| SCHEMBL23699358 | 0.80 | CTSS (0.47) | CTSSCTSKRIPK1PPARGPPARA | |
| SCHEMBL6320615 | 0.80 | CTSS (0.48) | CTSSCTSKRIPK1PTPN1PPARG | |
| SCHEMBL25185778 | 0.80 | CTSS (0.48) | CTSSCTSKRIPK1PTPN1PPARG | |
| SCHEMBL23699255 | 0.78 | CTSK (0.44) | CTSSCTSKPPARGHTR2CSLC6A4 | |
| SCHEMBL23719091 | 0.78 | CTSK (0.44) | CTSSCTSKPPARGHTR2CSLC6A4 | |
| SCHEMBL16798266 | 0.78 | PPARA (0.40) | PTPN1PPARGPPARAHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |