SCHEMBL23699504

SCHEMBL23699504

O=C(O)c1cc(S)ccc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
CYP3A4 P08684 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ASPH Q12797 1/20 0.42
KDM8 Q8N371 1/20 0.42
ALB P02768 1/20 0.41
MAPT P10636 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
KEAP1 Q14145 2/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
LMNA P02545 1/20 0.39
NFE2L2 Q16236 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
CASP1 P29466 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23242520 0.83 RARB (0.45) CES2CES1KDM4EASPHKDM8
SCHEMBL1431441 0.79 ALDH1A1 (0.48) CYP3A4KDM4EMAPTHDAC8ALDH1A1
SCHEMBL28640055 0.77 MAPT (0.54) CYP3A4KDM4EMAPTHDAC8ALDH1A1
SCHEMBL27793256 0.77 ALDH1A1 (0.46) CYP3A4KDM4EMAPTHDAC8ALDH1A1
SCHEMBL115334 0.77 CES2 (0.71) CES2CES1CYP3A4KDM4EASPH
SCHEMBL28742361 0.76 CES2 (0.68) CES2CES1CYP3A4KDM4EASPH
SCHEMBL283203 0.76 ALDH1A1 (0.65) CYP3A4KDM4EALBMRGPRX4KEAP1
SCHEMBL29798953 0.76 CES2 (0.68) CES2CES1CYP3A4KDM4EASPH
SCHEMBL336060 0.76 KDM4E (0.52) CES2CES1CYP3A4KDM4EASPH
SCHEMBL1264408 0.76 CA1 (0.61) CES2CES1CYP3A4KDM4EASPH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3859804-B1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KK (JP) 2024-08-07 EP claimed
CN-118146099-A Preparation method of 3-nitro-2-fluorobenzoic acid 张家港保税区三骏化工有限公司 2024-06-07 CN claimed
US-20250320204-A1 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS RIBOSCIENCE LLC (US) 2025-10-16 US disclosed
US-12245446-B2 Semiconductor device having quantum dots, display device, imaging system, and moving body CANON KABUSHIKI KAISHA (JP) 2025-03-04 US disclosed
EP-3859804-B1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KK (JP) 2024-08-07 EP disclosed
CN-113285024-A Semiconductor device having quantum dots, display device, imaging system, and moving object 佳能株式会社 2021-08-20 CN disclosed
US-20210242416-A1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS, DISPLAY DEVICE, IMAGING SYSTEM, AND MOVING BODY CANON KABUSHIKI KAISHA (JP) 2021-08-05 US disclosed
EP-3859804-A2 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KABUSHIKI KAISHA (JP) 2021-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250320204-A1 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS ENPP1, ENPP3, PDE7A CES2 1017/4885CES1 232/4885CYP3A4 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.