SCHEMBL23701037

SCHEMBL23701037

ClCCO[SiH2]c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
KCNA3 P22001 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27595496 0.79 TSHR (0.33)
SCHEMBL703559 0.77 LMNA (0.39) ALDH1A1MAPK1KCNA3
SCHEMBL28105891 0.77 TAAR1 (0.46) ALDH1A1MAPK1
SCHEMBL27560150 0.76 CA1 (0.42) ALDH1A1
SCHEMBL3298600 0.76 CA2 (0.41) ALDH1A1MAPK1
SCHEMBL28729613 0.74 KCNA3 (0.54) ALDH1A1KCNA3
SCHEMBL706853 0.74 LTA4H (0.47) ALDH1A1MAPK1
SCHEMBL3295135 0.72 MAPK1 (0.39) ALDH1A1MAPK1
SCHEMBL689761 0.72 LTA4H (0.47) ALDH1A1MAPK1KCNA3
SCHEMBL704392 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
CN-1837221-B Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO 2011-06-08 CN disclosed
CN-1296374-C Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2007-01-24 CN disclosed
CN-1837221-A Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO (JP) 2006-09-27 CN disclosed
CN-1612886-A Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2005-05-04 CN disclosed