SCHEMBL23701209

SCHEMBL23701209

CC(C)O[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9633947 0.82 TSHR (0.34) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL708488 0.76 ALDH1A1 (0.35) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL106923 0.76 TDP1 (0.37) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL106516 0.76 TSHR (0.36) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL705272 0.76 ESR1 (0.38) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL309052 0.74 ESR1 (0.37) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL705119 0.74 ESR1 (0.37) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL706260 0.74 ESR1 (0.37) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL704147 0.74 ALDH1A1 (0.34) NPSR1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL713414 0.74 ESR1 (0.37) NPSR1ALDH1A1L3MBTL1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed