Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701209 | 0.82 | NPSR1 (0.34) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL106516 | 0.81 | TSHR (0.36) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL705119 | 0.79 | ESR1 (0.37) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL705272 | 0.76 | ESR1 (0.38) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL106923 | 0.76 | TDP1 (0.37) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL708488 | 0.76 | ALDH1A1 (0.35) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL28390987 | 0.76 | TSHR (0.33) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL309052 | 0.74 | ESR1 (0.37) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL706260 | 0.74 | ESR1 (0.37) | TSHRALDH1A1L3MBTL1ESR1ESR2 | |
| SCHEMBL713414 | 0.74 | ESR1 (0.37) | TSHRALDH1A1L3MBTL1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210452-B1 | PROCESS FOR THE PREPARATION OF PARTIALLY ESTERIFIED SILICON HALIDES | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-05-06 | — | — | EP | disclosed |
| US-4677215-A | Method of preparing partially esterified silicon halides | DYNAMIT NOBEL AG (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0210452-A2 | Process for the preparation of partially esterified silicon halides | HÜLS AKTIENGESELLSCHAFT (DE) | 1987-02-04 | — | — | EP | disclosed |