SCHEMBL23701212

SCHEMBL23701212

CCCO[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 4/20 0.34
LTA4H P09960 2/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TP53 P04637 1/20 0.31
TLR8 Q9NR97 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
FGFR1 P11362 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4650379 0.88 LTA4H (0.44) ALDH1A1LTA4HSMN1; SMN2TLR8TSHR
SCHEMBL5305402 0.83 LMNA (0.37) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL18108386 0.83 LMNA (0.37) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL9499334 0.83 LTA4H (0.34) ALDH1A1LTA4HHPGDSMN1; SMN2TP53
SCHEMBL703110 0.78 DUT (0.42) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL105659 0.78 LMNA (0.39) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL106121 0.78 LMNA (0.39) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL426599 0.77 LMNA (0.38) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL704989 0.77 LMNA (0.38) LMNAMEN1KMT2AALDH1A1LTA4H
SCHEMBL706837 0.77 LMNA (0.38) LMNAMEN1KMT2AALDH1A1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed