SCHEMBL9499334

SCHEMBL9499334

CCO[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.34
TP53 P04637 2/20 0.33
RELA Q04206 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KCNH2 Q12809 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701212 0.83 LMNA (0.37) LTA4HTP53NPSR1ALDH1A1TSHR
SCHEMBL1130609 0.82 LTA4H (0.34) LTA4HTP53RELANPSR1ESR1
SCHEMBL4071553 0.82 LTA4H (0.34) LTA4HTP53RELANPSR1ESR1
SCHEMBL9633287 0.80 ESR1 (0.34) LTA4HTP53RELANPSR1ESR1
SCHEMBL4650379 0.79 LTA4H (0.44) LTA4HALDH1A1TSHRNPC1RAB9A
SCHEMBL18108006 0.78 LTA4H (0.32) LTA4HTP53
SCHEMBL18108289 0.78 LTA4H (0.32) LTA4HTP53
SCHEMBL645564 0.78 LTA4H (0.38) LTA4HTP53RELANPSR1ESR1
Chloromethane SCHEMBL27769943 0.77 LTA4H (0.34) LTA4HTP53RELANPSR1ESR1
SCHEMBL523641 0.77 LTA4H (0.31) LTA4HTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
US-9884928-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2018-02-06 US disclosed
US-20160289354-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
EP-0267794-B1 PROCESS FOR PREPARING POLYOLEFINS Nippon Petrochemicals Co., Ltd. (JP) 1993-05-05 EP disclosed
EP-0267794-A2 Process for preparing polyolefins Nippon Petrochemicals Co., Ltd. (JP) 1988-05-18 EP disclosed
US-4619981-A PULVERIZING MAGNESIUM HALIDE, SILANOL, AROMATIC ALCOHOL AND ETHER, POLYMERIZATION CATALYSTS NIPPON OIL COMPANY, LIMITED (JP) 1986-10-28 US disclosed
US-4537938-A POLYMERIZATION CATALYST NIPPON OIL COMPANY, LIMITED (JP) 1985-08-27 US disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed
US-4396534-A Olefin polymerizing catalyst NIPPON OIL COMPANY, LIMITED (JP) 1983-08-02 US disclosed