Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 3/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.48 |
| ▸ | KDM6B | O15054 | 2/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172335 | 1.00 | — | — | |
| SCHEMBL4600342 | 0.97 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL27527535 | 0.92 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL468549 | 0.87 | TSHR (0.44) | LMNAEGLN1KDM5CPHF8KDM2A | |
| SCHEMBL458277 | 0.83 | LMNA (0.58) | LMNAGABRR1TSHRSLC22A6THRB | |
| SCHEMBL13280352 | 0.83 | TSHR (0.58) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Adipic Acid SCHEMBL810759 | 0.83 | LMNA (0.58) | LMNAGABRR1TSHRSLC22A6THRB | |
| SCHEMBL11486379 | 0.81 | TSHR (0.60) | LMNATSHROR51E2SLC22A6THRB | |
| SCHEMBL17011633 | 0.81 | TSHR (0.60) | LMNATSHROR51E2SLC22A6THRB | |
| SCHEMBL11480082 | 0.81 | TSHR (0.60) | LMNATSHROR51E2SLC22A6THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230110819-A1 | BIO-BASED NYLON PRECURSORS HAVING REDUCED ORGANIC AND INORGANIC IMPURITIES | MOJIA BIOTECH LTD. (CN) | 2023-04-13 | — | — | US | disclosed |
| EP-4118224-A1 | BIO-BASED NYLON PRECURSORS HAVING REDUCED ORGANIC AND INORGANIC IMPURITIES | Mojia Biotech Ltd. (CN) | 2023-01-18 | — | — | EP | disclosed |
| CN-115181763-A | Bio-based nylon precursors with reduced inorganic ion content | 广安摩珈生物科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113122589-A | Bio-based nylon precursors with reduced inorganic ion content | 广安摩珈生物科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| EP-2496545-B1 | SULFOMETHYLSUCCINATES, PROCESS FOR MAKING SAME AND COMPOSITIONS CONTAINING SAME | STEPAN CO (US) | 2017-01-11 | — | — | EP | disclosed |
| US-8853141-B2 | Sulfomethylsuccinates, process for making same and compositions containing same | STEPAN COMPANY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120270764-A1 | SULFOMETHYLSUCCINATES, PROCESS FOR MAKING SAME AND COMPOSITIONS CONTAINING SAME | STEPAN COMPANY | 2012-10-25 | — | — | US | disclosed |
| EP-2496545-A2 | SULFOMETHYLSUCCINATES, PROCESS FOR MAKING SAME AND COMPOSITIONS CONTAINING SAME | Stepan Company (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011109047-A2 | SULFOMETHYLSUCCINATES, PROCESS FOR MAKING SAME AND COMPOSITIONS CONTAINING SAME | STEPAN COMPANY (US) | 2011-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270764-A1 | SULFOMETHYLSUCCINATES, PROCESS FOR MAKING SAME AND COMPOSITIONS CONTAINING SAME | ACMSD, SRMS, TST | LMNA 4368/4885EGLN1 3988/4885ALKBH5 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.