Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.48 |
| ▸ | CDK2 | P24941 | 9/20 | 0.48 |
| ▸ | CDK1 | P06493 | 3/20 | 0.48 |
| ▸ | CDK4 | P11802 | 3/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | OGA | O60502 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186141 | 0.86 | HCAR2 (0.53) | FFAR2CCNE1CDK2CDK1CDK4 | |
| SCHEMBL16113496 | 0.84 | CCNE1 (0.60) | CCNE1CDK2CDK1CDK4CCNE2 | |
| SCHEMBL4522999 | 0.84 | CCNE1 (0.59) | CCNE1CDK2CDK1CDK4CCNE2 | |
| SCHEMBL16607121 | 0.83 | AGER (0.59) | FFAR2RAB9ASMN1; SMN2MAPKAPK2 | |
| SCHEMBL23388184 | 0.81 | FFAR2 (0.48) | FFAR2RAB9ASMN1; SMN2MAPKAPK2 | |
| SCHEMBL5216255 | 0.81 | CCNE1 (0.46) | CCNE1CDK2CDK1CDK4CCNE2 | |
| SCHEMBL1131936 | 0.80 | FFAR2 (0.48) | FFAR2CCNE1CDK2CDK1CDK4 | |
| SCHEMBL31032966 | 0.80 | FFAR2 (0.48) | FFAR2CCNE1CDK2CCNE2CDK5 | |
| SCHEMBL3580537 | 0.79 | KDR (0.61) | FFAR2CCNE1CDK2CDK5RAB9A | |
| SCHEMBL5214094 | 0.78 | FFAR2 (0.49) | FFAR2RAB9ASMN1; SMN2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | TAKEDA CALIFORNIA, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | TAKEDA CALIFORNIA, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2547667-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | Takeda California, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011115758-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | TAKEDA SAN DIEGO, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | GFPT1, PFAS, PFKFB4 | FFAR2 896/4885CCNE1 100/4885CDK2 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.