Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.48 |
| ▸ | TPH1 | P17752 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16814938 | 0.98 | NCF1 (0.47) | NCF1TPH1BACE1TAAR1KDM4E | |
| SCHEMBL16793323 | 0.98 | NCF1 (0.47) | NCF1TPH1BACE1TAAR1KDM4E | |
| SCHEMBL23708106 | 0.84 | ALDH1A1 (0.43) | TPH1BACE1KDM4EL3MBTL1CHKA | |
| SCHEMBL23708502 | 0.78 | KEAP1 (0.56) | NCF1KDM4EL3MBTL1KEAP1ALDH1A1 | |
| SCHEMBL111729 | 0.77 | NCF1 (0.72) | NCF1KDM4EL3MBTL1KEAP1ALDH1A1 | |
| SCHEMBL27407320 | 0.76 | ALDH1A1 (0.58) | NCF1KDM4EL3MBTL1ALDH1A1LMNA | |
| SCHEMBL16814951 | 0.75 | NCF1 (0.70) | NCF1KDM4EL3MBTL1KEAP1ALDH1A1 | |
| SCHEMBL110730 | 0.75 | NCF1 (0.70) | NCF1KDM4EL3MBTL1KEAP1ALDH1A1 | |
| SCHEMBL16793140 | 0.75 | BACE1 (0.55) | BACE1KDM4ECHKAALDH1A1LMNA | |
| SCHEMBL18998517 | 0.75 | KMT2A (0.47) | KDM4EL3MBTL1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |