Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708171 | 0.84 | NCF1 (0.48) | ALDH1A1TPH1BACE1L3MBTL1MAPT | |
| SCHEMBL16793323 | 0.83 | NCF1 (0.47) | ALDH1A1TPH1BACE1L3MBTL1MAPT | |
| SCHEMBL16814938 | 0.83 | NCF1 (0.47) | ALDH1A1TPH1BACE1L3MBTL1MAPT | |
| SCHEMBL8776692 | 0.79 | NCF1 (0.54) | ALDH1A1L3MBTL1GAAMAPTNPSR1 | |
| SCHEMBL6514775 | 0.77 | KEAP1 (0.53) | L3MBTL1GAAMAPTNPSR1KMT2A | |
| SCHEMBL19203563 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TPH1GAAMAPTLMNA | |
| Nitrogen SCHEMBL4600854 | 0.75 | NCF1 (0.51) | ALDH1A1L3MBTL1GAAMAPTNPSR1 | |
| Methylamine SCHEMBL6478870 | 0.75 | NCF1 (0.56) | ALDH1A1L3MBTL1GAAMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL29156848 | 0.75 | KEAP1 (0.52) | L3MBTL1GAAMAPTNPSR1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7896018 | 0.75 | KEAP1 (0.52) | L3MBTL1GAAMAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |