Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708324 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ALDH1A3SMN1; SMN2MAPK1TSHR | |
| SCHEMBL23708525 | 0.78 | NR1I2 (0.43) | ALDH1A1ALDH1A3SMN1; SMN2MAPK1TSHR | |
| SCHEMBL28212779 | 0.77 | MEN1 (0.64) | ALDH1A1DHODHSMN1; SMN2TSHRKDM4E | |
| SCHEMBL7054984 | 0.75 | HTR7 (0.68) | HTR7ALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL27902948 | 0.73 | ALDH1A1 (0.61) | ALDH1A1DHODHSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL27625890 | 0.73 | ERN1 (0.57) | ALDH1A1DHODHSMN1; SMN2TSHRERN1 | |
| SCHEMBL23708632 | 0.73 | ALDH1A1 (0.62) | ALDH1A1ALDH1A3SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL15938805 | 0.72 | HTR7 (0.83) | HTR7MAPK1KDM4EMAPTDRD2 | |
| SCHEMBL3165674 | 0.71 | DRD2 (0.72) | ALDH1A1SMN1; SMN2MAPK1HPGDLMNA | |
| SCHEMBL8342531 | 0.71 | ALDH1A1 (0.61) | ALDH1A1ALDH1A3SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |