Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708148 | 0.79 | ALOX5 (0.52) | NR1I2SMARCA2SMARCA4PBRM1ALDH1A1 | |
| SCHEMBL23708532 | 0.78 | HTR7 (0.49) | ALDH1A1HPGDNPC1RAB9ALMNA | |
| SCHEMBL23708632 | 0.76 | ALDH1A1 (0.62) | ALDH1A1POLBRAB9ALMNAMAPK1 | |
| SCHEMBL28149235 | 0.75 | APP (0.72) | ALDH1A1APPPDK2CYP2A6 | |
| SCHEMBL28698328 | 0.72 | CNR2 (0.55) | CNR2CNR1ALDH1A1POLBHPGD | |
| SCHEMBL5409100 | 0.71 | NCF1 (0.60) | ALDH1A1LMNAMAPK1MAPTHTT | |
| SCHEMBL5842547 | 0.70 | CYP3A4 (0.57) | ALDH1A1POLBHPGDAPPPDK2 | |
| SCHEMBL1825806 | 0.70 | ADRB1 (0.65) | ALDH1A1POLBNSD2RAB9ALMNA | |
| SCHEMBL9655124 | 0.68 | ADRB1 (0.63) | ALDH1A1POLBNSD2NPC1RAB9A | |
| SCHEMBL10893618 | 0.68 | ADRB1 (0.63) | ALDH1A1POLBNSD2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |