Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480430 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPK1MAPTLMNAPOLB | |
| SCHEMBL23486528 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1GAAMAPT | |
| SCHEMBL23708525 | 0.76 | NR1I2 (0.43) | ALDH1A1MAPK1L3MBTL1MAPTLMNA | |
| SCHEMBL3485682 | 0.76 | MAPK1 (1.00) | ALDH1A1MAPK1L3MBTL1GAAMAPT | |
| SCHEMBL29655203 | 0.75 | TDP1 (0.64) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL13299014 | 0.74 | S1PR1 (0.50) | ALDH1A1MAPK1L3MBTL1GAAMAPT | |
| SCHEMBL29890979 | 0.73 | MAPT (0.55) | ALDH1A1MAPK1L3MBTL1GAAMAPT | |
| SCHEMBL29937743 | 0.73 | CTSB (0.65) | ALDH1A1MAPK1L3MBTL1GAAMAPT | |
| SCHEMBL3799173 | 0.73 | CTSB (0.65) | ALDH1A1MAPK1L3MBTL1GAAMAPT | |
| SCHEMBL23708532 | 0.73 | HTR7 (0.49) | ALDH1A1MAPK1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |