Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020137 | 1.00 | BCAT2 (0.50) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL28795375 | 0.87 | BCAT2 (0.47) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL28794373 | 0.81 | CYP1A2 (0.52) | MEN1KMT2ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL758247 | 0.79 | HPGD (0.45) | KMT2ASMN1; SMN2CYP1A2ALDH1A1HPGD | |
| SCHEMBL5008845 | 0.77 | BCAT2 (0.54) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL5572153 | 0.77 | BCAT2 (0.54) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL4870791 | 0.77 | BCAT2 (0.54) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL1034554 | 0.76 | BCAT2 (0.63) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL19802952 | 0.76 | BCAT2 (0.52) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL32689453 | 0.76 | BCAT2 (0.63) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139809-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| US-20230139809-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | US | disclosed |
| WO-2021151922-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139809-A1 | BENZIMIDAZOLE DERIVATIVES | ECI1, COX4I1, BRD4 | BCAT2 628/4885MEN1 4051/4885KMT2A 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.