SCHEMBL758247

SCHEMBL758247

N=C(c1ccccc1)c1ccccc1-c1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.45
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 2/20 0.45
BCL2L1 Q07817 1/20 0.45
CYP1A2 P05177 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.39
KDM4E B2RXH2 3/20 0.39
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA1 P00915 1/20 0.39
HMGB1 P09429 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
F2 P00734 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50746 0.83 HPGD (0.50) HPGDALDH1A1HSD17B10CYP1A2SMN1; SMN2
SCHEMBL31020137 0.79 BCAT2 (0.50) HPGDALDH1A1HSD17B10BCL2L1CYP1A2
SCHEMBL23709161 0.79 BCAT2 (0.50) HPGDALDH1A1HSD17B10BCL2L1CYP1A2
SCHEMBL28794373 0.78 CYP1A2 (0.52) HPGDALDH1A1HSD17B10CYP1A2SMN1; SMN2
SCHEMBL29542253 0.76 AKR1C3 (0.55) HPGDALDH1A1HSD17B10BCL2L1CYP1A2
SCHEMBL92723 0.76 AKR1C3 (0.55) HPGDALDH1A1HSD17B10BCL2L1CYP1A2
Hydrochloric Acid SCHEMBL9156565 0.73 ALDH1A1 (0.43) HPGDALDH1A1HSD17B10BCL2L1SMN1; SMN2
SCHEMBL3676607 0.73 HTR7 (0.46) CYP1A2CA2CA4CA1CA6
SCHEMBL11085072 0.72 ALDH1A1 (0.50) HPGDALDH1A1HSD17B10BCL2L1SMN1; SMN2
SCHEMBL1919550 0.72 ALDH1A1 (0.67) HPGDALDH1A1HSD17B10BCL2L1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2669342-B1 ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK, AND INKJET RECORDING METHOD KONICA MINOLTA INC (JP) 2020-03-18 EP disclosed
US-9416289-B2 Active-energy-ray-curable inkjet ink composition, active-energy-ray-curable inkjet ink, and inkjet recording method Konica Minolta, Inc. (JP) 2016-08-16 US disclosed
EP-2669342-A1 ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK, AND INKJET RECORDING METHOD Konica Minolta, Inc. (JP) 2013-12-04 EP disclosed
US-20130307913-A1 ACTIVE-ENERGY-RAY-CURABLE INKJET INK COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE INKJET INK, AND INKJET RECORDING METHOD Konica Minolta, Inc. (JP) 2013-11-21 US disclosed
US-8349916-B2 Actinic energy radiation curable ink-jet ink, ink-jet recording method, and printed matter KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2013-01-08 US disclosed
EP-2228415-B1 Actinic energy radiation curable ink-jet ink, ink-jet recoring method, and printed matter KONICA MINOLTA IJ TECHNOLOGIES (JP) 2012-03-21 EP disclosed
US-20100255211-A1 ACTINIC ENERGY RADIATION CURABLE INK-JET INK AND INK-JET IMAGE FORMING METHOD KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2010-10-07 US disclosed
EP-2236568-A1 Actinic energy radiation curable ink-jet ink and ink-jet image forming method Konica Minolta IJ Technologies, Inc. (JP) 2010-10-06 EP disclosed
US-20100233446-A1 ACTINIC ENERGY RADIATION CURABLE INK-JET INK, INK-JET RECORDING METHOD, AND PRINTED MATTER KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2010-09-16 US disclosed
EP-2228415-A1 Acting energy radiation curable ink-jet ink, ink-jet recoring method, and printed matter Konica Minolta IJ Technologies, Inc. (JP) 2010-09-15 EP disclosed
US-20060287548-A1 Radical interceptors as stabilizers of polymerizable compounds BASF AKTIENGESELLSCHAFT (DE) 2006-12-21 US disclosed
CN-1878852-A Radical trap as a stabilizer for polymerizable compounds BASF AG (DE) 2006-12-13 CN disclosed
CN-1705872-A Method for determining the amount of polymer separated from acrylic acid and/or acrylic esters BASF AG (DE) 2005-12-07 CN disclosed
US-20040082737-A1 Determination of the amount of polymer deposited from (meth) acrylic acid and/or (meth) acrylic esters BASF AKTIENGESELLSCHAFT (DE) 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287548-A1 Radical interceptors as stabilizers of polymerizable compounds TTPA, AADAT, TSPO HPGD 209/4885ALDH1A1 1648/4885HSD17B10 3372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.