Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27099546 | 0.84 | ALDH1A1 (0.64) | ALDH1A1CYP2C19NPSR1CYP1A2MAPT | |
| SCHEMBL7914803 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP2C19NPSR1MAPTCDK1 | |
| SCHEMBL8553879 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP2C19NPSR1MAPTCDK1 | |
| SCHEMBL4570273 | 0.79 | ALDH1A1 (0.54) | ALDH1A1CYP2C19NPSR1MAPK1MAPT | |
| SCHEMBL17844454 | 0.70 | ALDH1A1 (0.49) | ALDH1A1CYP2C19NPSR1MAPTCDK1 | |
| SCHEMBL12284639 | 0.70 | ALDH1A1 (0.65) | ALDH1A1NPSR1CYP1A2MAPK1MAPT | |
| SCHEMBL718210 | 0.70 | NPSR1 (0.52) | ALDH1A1NPSR1CYP1A2MAPK1MAPT | |
| SCHEMBL14342224 | 0.69 | ALDH1A1 (0.44) | ALDH1A1CYP2C19CYP1A2MAPTCDK1 | |
| SCHEMBL27903732 | 0.68 | ALDH1A1 (0.53) | ALDH1A1CYP2C19MAPTKMT2AKDM4E | |
| SCHEMBL19506131 | 0.68 | XDH (0.46) | ALDH1A1CYP2C19NPSR1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238213-A1 | SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING N6-(2-DEOXY-ALPHA,BETA-DERYTHROPENTOFURANOSYL)-2,6-DIAMINO-4-HYDROXY-5-FORMAMIDOPYRIMIDINE (Fapy.dG) | THE JOHNS HOPKINS UNIVERSITY | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238213-A1 | SOLID-PHASE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING N6-(2-DEOXY-ALPHA,BETA-DERYTHROPENTOFURANOSYL)-2,6-DIAMINO-4-HYDROXY-5-FORMAMIDOPYRIMIDINE (Fapy.dG) | DPYD, TYMP, RNGTT | ALDH1A1 2366/4885CYP2C19 4574/4885NPSR1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.