SCHEMBL2371547

SCHEMBL2371547

[CH2]NS(=O)(=O)c1ccccc1OC

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.55
KAT6A Q92794 1/20 0.49
ACLY P53396 1/20 0.48
SLC40A1 Q9NP59 1/20 0.48
SLC22A12 Q96S37 1/20 0.46
NPC1 O15118 1/20 0.45
TSHR P16473 1/20 0.45
ITGAV P06756 1/20 0.45
PKM P14618 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
BRD4 O60885 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
NFE2L2 Q16236 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29965203 0.82 L3MBTL1 (0.61) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL2371550 0.82 L3MBTL1 (0.61) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL28146316 0.81 HTR6 (0.55) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL28844042 0.81 HTR6 (0.55) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL8224006 0.81 HTR6 (0.55) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL5501632 0.81 HTR6 (0.55) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL28146309 0.81 HTR6 (0.55) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL29288590 0.81 HTR6 (0.55) HTR6KAT6AACLYSLC40A1SLC22A12
SCHEMBL28593071 0.80 SMN1; SMN2 (0.50) HTR6KAT6AACLYSLC40A1ITGAV
SCHEMBL3575927 0.79 HTR6 (0.53) HTR6KAT6AACLYSLC40A1SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST HTR6 1828/4885KAT6A 2457/4885ACLY 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.