Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695942 | 0.84 | CASP1 (0.42) | HTR6CA1CA2CA12CA7 | |
| SCHEMBL128257 | 0.84 | CASP1 (0.42) | HTR6CA1CA2CA12CA7 | |
| SCHEMBL2371550 | 0.82 | L3MBTL1 (0.61) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL29965203 | 0.82 | L3MBTL1 (0.61) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL28146316 | 0.81 | HTR6 (0.55) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL28844042 | 0.81 | HTR6 (0.55) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL2371547 | 0.81 | HTR6 (0.55) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL28146309 | 0.81 | HTR6 (0.55) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL29288590 | 0.81 | HTR6 (0.55) | HTR6KAT6AACLYSLC40A1SLC22A12 | |
| SCHEMBL8224006 | 0.81 | HTR6 (0.55) | HTR6KAT6AACLYSLC40A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507866-B | Electrochemical-mediated synthesis method of 2-arylbenzofuran compound | 南京先进生物材料与过程装备研究院有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-114507866-A | Electrochemical-mediated synthesis method of 2-arylbenzofuran compounds | 南京先进生物材料与过程装备研究院有限公司 | 2022-05-17 | — | — | CN | claimed |
| EP-1320523-B1 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | WARNER-LAMBERT COMPANY LLC | 2005-01-06 | — | — | US | claimed |
| EP-1320523-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Warner-Lambert Company LLC (US) | 2003-06-25 | — | — | EP | claimed |
| WO-2002024672-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER-LAMBERT COMPANY LLC (US) | 2002-03-28 | — | — | WO | claimed |
| US-12559455-B2 | Compound as a UBR box domain ligand | AUTOTAC INC. (KR) | 2026-02-24 | — | — | US | disclosed |
| CN-114507866-B | Electrochemical-mediated synthesis method of 2-arylbenzofuran compound | 南京先进生物材料与过程装备研究院有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114507866-B | Electrochemical-mediated synthesis method of 2-arylbenzofuran compound | 南京先进生物材料与过程装备研究院有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| CN-113214129-B | Method for iodination/sulfonylation reaction of 1, 6-diene compound initiated by sulfonyl free radical | 怀化学院 | 2022-06-24 | — | — | CN | disclosed |
| CN-114507866-A | Electrochemical-mediated synthesis method of 2-arylbenzofuran compounds | 南京先进生物材料与过程装备研究院有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114507866-A | Electrochemical-mediated synthesis method of 2-arylbenzofuran compounds | 南京先进生物材料与过程装备研究院有限公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-1998002750-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | BIOTRACES, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| EP-0055087-B1 | COMPOSITIONS AND METHODS FOR PRODUCING EXPANDED AND CURED POLYESTER RESIN | UNIROYAL, INC. (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4525487-A | FROM USATURATED POLYESTER SULFONYL HYDRAZIDE, PROMOTER, CATALYST, AND QATERNARY AMMONIUM SALT | UNIROYAL, INC. (US) | 1985-06-25 | — | — | US | disclosed |
| EP-0101197-A2 | Method for preparing foam using cobalt/potassium promoters | UNIROYAL, INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4401771-A | HYDROCARBYLSULFONYL HYDRAZIDE FOAMING AGENT | UNIROYAL, INC. (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0055087-A1 | Compositions and methods for producing expanded and cured polyester resin | UNIROYAL, INC. (US) | 1982-06-30 | — | — | EP | disclosed |
| US-4327196-A | USING SULFONYL HYDRAZIDE BLOWING AGENTS, PEROXIDE CURING AGENTS FOR SIMULTANEOUS FOAMING AND CURING | UNIROYAL, INC. (US) | 1982-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | BCAT1, BCAT2, ABAT | HTR6 837/4885KAT6A 1615/4885ACLY 639/4885 |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | UBR4, UBQLN2, UBTF | HTR6 2638/4885KAT6A 1150/4885ACLY 4085/4885 |
| US-12559455-B2 | Compound as a UBR box domain ligand | UBR4, UBTF, UBQLN1 | HTR6 561/4885KAT6A 607/4885ACLY 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.