Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716330 | 0.77 | MDM2 (0.38) | ALDH1A1LMNAKDM4ESLC6A4HTR2A | |
| SCHEMBL23716419 | 0.71 | SLC6A3 (0.35) | ALDH1A1KDM4ESLC6A4HTR2AKCNH2 | |
| SCHEMBL9152734 | 0.71 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ESLC6A4HTR2A | |
| SCHEMBL7679890 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1LMNAKDM4ESLC6A4HTR2A | |
| SCHEMBL7673452 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1LMNAKDM4ESLC6A4HTR2A | |
| SCHEMBL7679892 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1LMNAKDM4ESLC6A4HTR2A | |
| SCHEMBL23716290 | 0.67 | SLC6A4 (0.38) | ALDH1A1LMNAKDM4ESLC6A4HTR2A | |
| SCHEMBL7318571 | 0.65 | PPARG (0.41) | ALDH1A1LMNAKDM4EJAK2PPARG | |
| SCHEMBL11068943 | 0.65 | PPARG (0.41) | ALDH1A1LMNAKDM4EJAK2PPARG | |
| SCHEMBL10668698 | 0.65 | MMP8 (0.51) | ALDH1A1LMNAKDM4ESLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |