Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716117 | 0.74 | OGG1 (0.38) | SLC6A4HTR2AKCNH2FFAR1PNMT | |
| SCHEMBL23716330 | 0.68 | MDM2 (0.38) | SLC6A4SLC6A2HTR2AKCNH2S1PR3 | |
| SCHEMBL23716123 | 0.68 | AOC3 (0.42) | ALDH1A1KDM4ELMNA | |
| SCHEMBL23716190 | 0.68 | SLC6A3 (0.41) | SLC6A3KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL23715786 | 0.67 | ALDH1A1 (0.41) | SLC6A4HTR2AKCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL23715928 | 0.66 | IDO1 (0.39) | ALDH1A1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL257844 | 0.63 | HSP90AA1 (0.57) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL9152734 | 0.62 | ALDH1A1 (0.46) | SLC6A4HTR2AKCNH2ALDH1A1HSP90AA1 | |
| SCHEMBL7318571 | 0.59 | PPARG (0.41) | SLC6A3FFAR1ALDH1A1HSP90AA1PNMT | |
| SCHEMBL11068943 | 0.59 | PPARG (0.41) | SLC6A3FFAR1ALDH1A1HSP90AA1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |