Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.32 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716123 | 0.85 | AOC3 (0.42) | ALDH1A1AOC3KDM4E | |
| SCHEMBL23715793 | 0.78 | SYK (0.45) | IDO1TDO2KMT2AMAOBFNTA | |
| SCHEMBL23716117 | 0.76 | OGG1 (0.38) | MAOBAOC3 | |
| SCHEMBL23716135 | 0.68 | KMT2A (0.37) | KMT2AALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL23716290 | 0.66 | SLC6A4 (0.38) | KMT2AALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL23715980 | 0.65 | AOC3 (0.32) | AOC3 | |
| SCHEMBL7885157 | 0.65 | KMT2A (0.54) | KMT2AMAOBALDH1A1KDM4ECYP1A2 | |
| SCHEMBL20612473 | 0.63 | IDO1 (0.48) | IDO1TDO2ALDH1A1 | |
| SCHEMBL7145139 | 0.62 | IDO1 (0.45) | IDO1TDO2KMT2AALDH1A1KDM4E | |
| SCHEMBL23716036 | 0.62 | AOC3 (0.50) | KMT2AALDH1A1HSD17B10AOC3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |