Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716193 | 0.78 | OGG1 (0.44) | OGG1WDR5CNR1CNR2PTGER4 | |
| SCHEMBL23716123 | 0.76 | AOC3 (0.42) | AOC3 | |
| SCHEMBL23715928 | 0.76 | IDO1 (0.39) | MAOBAOC3 | |
| SCHEMBL23716290 | 0.74 | SLC6A4 (0.38) | SLC6A4PNMTFFAR1PPARGHTR2A | |
| SCHEMBL23716102 | 0.72 | S1PR3 (0.40) | CNR1CNR2SLC6A4 | |
| SCHEMBL23716111 | 0.71 | OGG1 (0.45) | OGG1WDR5SLC6A4 | |
| SCHEMBL23715916 | 0.70 | OGG1 (0.44) | OGG1WDR5SLC6A4 | |
| SCHEMBL23715998 | 0.69 | S1PR3 (0.42) | SLC6A4 | |
| SCHEMBL23716312 | 0.68 | S1PR3 (0.52) | — | |
| SCHEMBL23716135 | 0.68 | KMT2A (0.37) | CNR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |