Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715793 | 0.88 | SYK (0.45) | KMT2ASYKCYP1A2GAAMAPT | |
| SCHEMBL23716193 | 0.88 | OGG1 (0.44) | KMT2APOLBPPARGALDH1A1PARP1 | |
| SCHEMBL23716330 | 0.81 | MDM2 (0.38) | KMT2AMEN1PPARGNPC1ALDH1A1 | |
| SCHEMBL23715916 | 0.81 | OGG1 (0.44) | CYP1A2GAAMAPTALDH1A1 | |
| SCHEMBL23716111 | 0.79 | OGG1 (0.45) | SYKPARP1 | |
| SCHEMBL23715975 | 0.70 | SIRT1 (0.42) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23716117 | 0.68 | OGG1 (0.38) | PPARGCNR1 | |
| SCHEMBL23715928 | 0.68 | IDO1 (0.39) | KMT2ACYP1A2GAAMAPTRECQL | |
| SCHEMBL23715777 | 0.66 | GPR88 (0.42) | — | |
| SCHEMBL23716167 | 0.65 | FFAR2 (0.47) | CYP1A2NPC1ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |