Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 4/20 | 0.37 |
| ▸ | METAP1 | P53582 | 3/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23715928 | 0.85 | IDO1 (0.39) | AOC3KDM4EALDH1A1 | |
| SCHEMBL23716117 | 0.76 | OGG1 (0.38) | AOC3 | |
| SCHEMBL23715980 | 0.73 | AOC3 (0.32) | AOC3 | |
| SCHEMBL23716036 | 0.70 | AOC3 (0.50) | AOC3ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL23716290 | 0.68 | SLC6A4 (0.38) | LMNAKDM4EALDH1A1 | |
| SCHEMBL23715777 | 0.65 | GPR88 (0.42) | METAP2METAP1LMNA | |
| SCHEMBL23715821 | 0.61 | GPR88 (0.43) | ALDH1A1 | |
| SCHEMBL453395 | 0.61 | DPP4 (0.52) | AOC3ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL7047936 | 0.61 | KDM4E (0.65) | AOC3ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL4451068 | 0.61 | DPP4 (0.52) | AOC3ADRA2AADRA2CLMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |