Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166423 | 0.79 | BACE1 (0.42) | DHFRBACE1MEN1GAAKMT2A | |
| SCHEMBL4683962 | 0.75 | CA2 (0.50) | DHFRBACE1 | |
| SCHEMBL23715780 | 0.75 | IDO1 (0.42) | GAAKMT2A | |
| SCHEMBL23716267 | 0.75 | SLC6A4 (0.34) | BACE1GAAKMT2A | |
| SCHEMBL23715988 | 0.74 | IDO1 (0.40) | — | |
| SCHEMBL23716015 | 0.73 | PTPN7 (0.34) | KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL23716362 | 0.73 | IDO1 (0.39) | SMN1; SMN2 | |
| SCHEMBL11041895 | 0.70 | HPGD (0.53) | MEN1GAAKMT2A | |
| SCHEMBL4683959 | 0.68 | DHFR (0.38) | DHFRBACE1GAAKMT2AALOX15 | |
| SCHEMBL27999728 | 0.68 | IAPP (0.41) | DHFRBACE1GAAKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |