Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716176 | 0.87 | IDO1 (0.40) | LMNAGAACRHBPCRHR2 | |
| SCHEMBL23716069 | 0.75 | DHFR (0.36) | BACE1KMT2AGAA | |
| SCHEMBL23715780 | 0.73 | IDO1 (0.42) | LMNAKMT2AGAACRHBPCRHR2 | |
| SCHEMBL23715862 | 0.72 | IDO1 (0.41) | LMNAKMT2AGAACRHBPCRHR2 | |
| SCHEMBL23716370 | 0.71 | IDO1 (0.44) | LMNAKMT2AGAACRHBPCRHR2 | |
| SCHEMBL23716186 | 0.71 | IDO1 (0.41) | LMNAHSP90AA1KMT2AGAACRHBP | |
| SCHEMBL23716015 | 0.71 | PTPN7 (0.34) | ALDH1A1KMT2AL3MBTL1CRHBPCRHR2 | |
| SCHEMBL23715869 | 0.70 | SMN1; SMN2 (0.33) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3790563 | 0.69 | TRPA1 (0.43) | SLC6A4HTR2ABACE1CSNK2A2CSNK2B | |
| SCHEMBL23716287 | 0.69 | ANO1 (0.34) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |