Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716102 | 0.80 | S1PR3 (0.40) | S1PR3S1PR4SLC6A4CNR2 | |
| SCHEMBL23715998 | 0.77 | S1PR3 (0.42) | S1PR3S1PR4SLC6A4MEN1KMT2A | |
| SCHEMBL23715847 | 0.76 | S1PR3 (0.42) | S1PR3S1PR4 | |
| SCHEMBL23716123 | 0.67 | AOC3 (0.42) | LMNAALDH1A1 | |
| SCHEMBL17664408 | 0.65 | DPP4 (0.45) | LMNAALDH1A1S1PR3S1PR4KMT2A | |
| SCHEMBL23715928 | 0.64 | IDO1 (0.39) | SMN1; SMN2ALDH1A1KMT2AFNTAFNTB | |
| SCHEMBL20428535 | 0.62 | MEN1 (0.46) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23715855 | 0.62 | GAA (0.40) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL17664411 | 0.62 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1S1PR3S1PR4 | |
| SCHEMBL17663900 | 0.62 | S1PR3 (0.60) | LMNASMN1; SMN2ALDH1A1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |